PeproTech重組人IGF-Binding Protein，貨號：350-10
PeproTech重組人IGF-Binding Protein，貨號：350-10
PeproTech重組人IGF-Binding Protein，貨號：350-10
品牌： PeproTech
產(chǎn)地： 美國
貨號： 350-10
保存條件： -20℃
規(guī)格：5μg/25μg/1mg
供應商： 深圳子科生物科技有限公司
數(shù)量： 大量
英文名： Recombinant Human IGF-Binding Protein 1
保質(zhì)期： 1年以上
|
Synonyms :
|
Insulin-like Growth Factor-Binding Protein 1, IBP-1, Placenta Protein 12 (PP12)
|
|
Description :
|
IGF-BPs controls the distribution, function and activity of IGFs in various cell tissues and body fluids. Currently there are seven named IGF-BPs that form high affinity complexes with both IGF-I and IGF-II. IGF-BP1 is a 25.4 kDa cysteine-rich secreted protein expressed in liver, deciduas, and kidneys and is the most abundant IGF-BP in amniotic fluid. Levels of IGF-BP1 in serum are lowest after food. IGF-BP1 binds to both IGF-I and IGF-II with equal affinity. Phosphorylated IGF-BP1 hinders IGF actions, where as nonphosphorylated IGF-BP1 is stimulatory. Recombinant human IGF-BP1 is a 25.4 kDa protein consisting of 235 amino acid residues (Isoform A).
|
|
Catalog #:
|
350-10
|
|
Source :
|
E.coli
|
|
Purity :
|
Greater than 98% by SDS-PAGE gel and HPLC analyses
|
|
Endotoxin Level :
|
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
|
|
Biological Activity :
|
The ED 50 was determined by its ability to inhibit IGF-I induced proliferation of MCF-7 is ≤ 0.5 μg/ml in the presence of 6 ng/ml of human IGF-I.
|
|
AA Sequence :
|
MAPWQCAPCS AEKLALCPPV SASCSEVTRS AGCGCCPMCA LPLGAACGVA TARCARGLSC RALPGEQQPL HALTRGQGAC VQESDASAPH AAEAGSPESP ESTEITEEEL LDNFHLMAPS EEDHSILWDA ISTYDGSKAL HVTNIKKWKE PCRIELYRVV ESLAKAQETS GEEISKFYLP NCNKNGFYHS RQCETSMDGE AGLCWCVYPW NGKRIPGSPE IRGDPNCQIY FNVQN
|
|
PubMed Link :
|
IGF+AND+Binding+AND+Protein+AND+1
|
|
Country of Origin :
|
USA
|
|
|
|
|
|
|
|
|
|
|
|
Special Sizes:
Many products can be ordered in custom sizes. Please click here to contact with your request.
|
|
|
Usage:
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
|
